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Table 4 Results of the algorithm in GBM1.

From: Identifying overlapping mutated driver pathways by constructing gene networks in cancer

Optimal gene sets Gene number Exclusivity Coverage P-value
CDKN2B, CYP27B1, RB1, ERBB2 4 90.9% 83.3% 6.46e-03
CDKN2A, TP53 2 90.8% 70.2% 5.33e-04
EGFR, NF1, KIT 3 93.4% 67.9% 4.99e-03
CDK4, MTAP, RB1, ERBB2 4 92.5% 73.8% 2.16e-05
PIK3CA, PTEN 2 90.4% 56.0% 9.91e-04
MDM2, NF1, PIK3R1 3 90.9% 47.6% 7.90e-03
DPYSL4, PDGFRA, PTEN, ERBB2 4 92.2% 56.0% 5.88e-05