Table 4 Results of the algorithm in GBM1.
From: Identifying overlapping mutated driver pathways by constructing gene networks in cancer
Optimal gene sets | Gene number | Exclusivity | Coverage | P-value |
|---|---|---|---|---|
CDKN2B, CYP27B1, RB1, ERBB2 | 4 | 90.9% | 83.3% | 6.46e-03 |
CDKN2A, TP53 | 2 | 90.8% | 70.2% | 5.33e-04 |
EGFR, NF1, KIT | 3 | 93.4% | 67.9% | 4.99e-03 |
CDK4, MTAP, RB1, ERBB2 | 4 | 92.5% | 73.8% | 2.16e-05 |
PIK3CA, PTEN | 2 | 90.4% | 56.0% | 9.91e-04 |
MDM2, NF1, PIK3R1 | 3 | 90.9% | 47.6% | 7.90e-03 |
DPYSL4, PDGFRA, PTEN, ERBB2 | 4 | 92.2% | 56.0% | 5.88e-05 |