Skip to main content

Table 5 Results of the algorithm in GBM2.

From: Identifying overlapping mutated driver pathways by constructing gene networks in cancer

Optimal gene sets Gene number Exclusivity Coverage P-value
CDKN2A, TP53, CDK4, RB1 4 82.4% 83.3% 2.64e-08
PTEN, PIK3CA, EGFR 3 86.7% 57.8% 1.17e-05
CDK4, CDKN2B, RB1 3 95.7% 73.3% 7.62e-05
PIK3CA, PTEN, PIK3R1 3 96.0% 53.3% 1.17e-05
MDM4, QKI, TP53, MDM2 4 93.2% 45.6% 2.74e-05
MDM2, TP53, PIK3R1, CPT1B 4 90.9% 44.4% 1.08e-04
CYP27B1, EGFR, NF1, PIK3R1 4 90.2% 51.1% 5.32e-04