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Table 5 Results of the algorithm in GBM2.

From: Identifying overlapping mutated driver pathways by constructing gene networks in cancer

Optimal gene sets

Gene number

Exclusivity

Coverage

P-value

CDKN2A, TP53, CDK4, RB1

4

82.4%

83.3%

2.64e-08

PTEN, PIK3CA, EGFR

3

86.7%

57.8%

1.17e-05

CDK4, CDKN2B, RB1

3

95.7%

73.3%

7.62e-05

PIK3CA, PTEN, PIK3R1

3

96.0%

53.3%

1.17e-05

MDM4, QKI, TP53, MDM2

4

93.2%

45.6%

2.74e-05

MDM2, TP53, PIK3R1, CPT1B

4

90.9%

44.4%

1.08e-04

CYP27B1, EGFR, NF1, PIK3R1

4

90.2%

51.1%

5.32e-04