Improving multiple sequence alignment by using better guide trees

BMC Bioinformatics

Table 3 Mean SP and TC scores on BAliBASE

		ClustalW		MSAProbs		Probalign		ProbCons		T-Coffee
		Adaptive	Original	Adaptive	Original	Adaptive	Original	Adaptive	Original	Adaptive	Original
SP	0%-60%	71.277	69.578	82.683	82.370	83.153	82.991	82.007	81.541	81.646	80.759
	0%-30%	52.878	51.573	69.251	68.584	70.183	69.826	68.289	67.300	67.543	65.676
	30%-60%	86.404	84.382	93.727	93.704	93.818	93.816	93.287	93.251	93.242	93.160
TC	0%-60%	51.865	49.121	67.449	67.274	68.054	67.691	66.284	65.618	66.457	64.894
	0%-30%	26.754	26.014	46.546	46.143	47.989	47.178	44.776	43.332	45.122	42.346
	30%-60%	72.511	68.120	84.636	84.649	84.551	84.558	83.969	83.942	84.000	83.433

Average SP score and average TC score of the alignments on BaliBASE3 generated by the five aligners with guide tree generated by adaptive method and by aligners' own. Rows show the average sum of pairs scores (SP) and total column scores (TC) multiplied by 100. The best results in each pair are shown in bold.

ISSN: 1471-2105