Figure 1From: Kissing loop interaction in adenine riboswitch: insights from umbrella sampling simulationsMechanism of action of A-riboswitch Cartoon showing the OFF (left) and ON (right) states of the A-riboswitch. When ligand is not present the ribosome binding site (orange, RBS) is paired with a portion of the aptamer and translation is blocked. When ligand is present the RBS is free to interact with the ribosome and translation can be initiated.Back to article page