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Table 1

From: An algorithm for mapping positively selected members of quasispecies-type viruses

Amino Acid Mutation(s) Obs. Exp. R:S Obs. R:S Selection
Phe (silent) ttt→ttc 10 na na na*
Tyr ttt→tat (Tyr) 24 1:1 24:10 positive (p = 0.02)
Ile ttt→att 1 1:1 1:10 negative (p = 0.01)
Leu ttt→tta or 3 3:1 3:10 negative (p = 0.0001)
  ttt→ttg or     
  ttt→ctt     
Val ttt→gtt 4 1:1 4:10 neutral (p = 0.18)
Ser ttt→tct 23 1:1 23:10 positive (p = 0.04)
Cys ttt→tgt 0 1:1 0:10 negative (p = 0.002)
  1. *neutral by definition