Table 1
From: An algorithm for mapping positively selected members of quasispecies-type viruses
Amino Acid | Mutation(s) | Obs. | Exp. R:S | Obs. R:S | Selection |
|---|---|---|---|---|---|
Phe (silent) | ttt→ttc | 10 | na | na | na* |
Tyr | ttt→tat (Tyr) | 24 | 1:1 | 24:10 | positive (p = 0.02) |
Ile | ttt→att | 1 | 1:1 | 1:10 | negative (p = 0.01) |
Leu | ttt→tta or | 3 | 3:1 | 3:10 | negative (p = 0.0001) |
|  | ttt→ttg or |  |  |  |  |
|  | ttt→ctt |  |  |  |  |
Val | ttt→gtt | 4 | 1:1 | 4:10 | neutral (p = 0.18) |
Ser | ttt→tct | 23 | 1:1 | 23:10 | positive (p = 0.04) |
Cys | ttt→tgt | 0 | 1:1 | 0:10 | negative (p = 0.002) |