Figure 2
From: Homology Induction: the use of machine learning to improve sequence similarity searches
The three ROC curves produced by PSI-BLAST, HIall, and HIseq for predictions in the twilight zone. While the ROC curve for PSI-BLAST results from applying ROC analysis directly to the results produced, the ROC curves for both HI methods are maximized using an optimal value for re-sorting. The ROC curve for HIall dominates over the other two curves at all times; while the curves for PSI-BLAST and HIseq oscillate around each other. HIseq dominates the PSI-BLAST curve between ~0.38 and ~0.5.