Table 3 Reduced expression in older muscle of genes involved in energy metabolism (ER = expression ratio = mean value in old / mean value in young)
From: Computational method for reducing variance with Affymetrix microarrays
Gene | ER signal method | ER ratio method | P signal method | P ratio method |
|---|---|---|---|---|
ubiquinol cytochrome c reductase binding protein | .72 | .73 | .0009 | .0015 |
cytochrome c oxidase Vb | .65 | .76 | .0214 | .0021 |
cytochrome bc-1 complex core protein II | .82 | .77 | .0137 | .0022 |
mitochondrial ADP/ATP translocator | .74 | .74 | .0036 | .0016 |
cytochrome c oxidase VIIc | .61 | .75 | .0026 | .0032 |
ATP synthase subunit F6 | .74 | .72 | .0078 | .0006 |
cytochrome c oxidase VIc | .78 | .79 | .0252 | .0016 |
cytochrome c oxidase VIIb | .69 | .73 | .0021 | .0019 |
adenylate kinase 1 | .76 | .76 | .0155 | .0003 |
ubiquinol cytochrome c reductase hinge protein | .71 | .72 | .0082 | .0041 |
holocytochrome c-type synthase | .77 | .81 | .0016 | .0046 |
cytochrome c oxidase VIIa2 | .73 | .73 | .0099 | .0062 |
NADH dehydrogenase KFYI | .83 | .87 | .0199 | .0098 |
mitochondrial aspartate aminotransferase | .72 | .76 | .0079 | .0100 |
cytochrome c oxidase 4 | .81 | .82 | .0057 | .0104 |
cytochrome c | .69 | .70 | .0016 | .0108 |
ATP synthase c (P1 gene) | .75 | .77 | .0052 | .0112 |