Figure 8

Comparison of results between constant normalization and curve normalization. The two data sets were both genomics DNA samples of the same yeast strain (s288c) collected using the YG_S98 Affymetrix array in about 50 days period. The intensities of the 70 percentile of each probe set were used in the Log-scale plot. Results for constant normalization and curve normalization are shown in green and red pixels, respectively. Yellow dots are shown where the pixel is colored by both red and green. As it shows, the two methods give essentially the same results for lower intensity regions, while curve normalization seems to be able to correct non-linearity better in the high intensity end.