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Figure 6 | BMC Bioinformatics

Figure 6

From: Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases

Figure 6

Comparison of DNA contacts in APE1 and DNase 1. Comparison of the DNA-contact plots of huAPE1 with product (cleaved DNA, from the 1DE9 structure) and DNase 1 (uncleaved substrate, from 1DNK) illustrates the similar mode of binding by the areas conserved between the two proteins. The scissile bonds in both DNAs, 5' of the abasic site in APE1, C315 in 1DNK [53], are indicated by arrows.

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BMC Bioinformatics

ISSN: 1471-2105

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