Figure 3

Unsupervised hierarchical clustering of 24 human MuscleChip Affymetrix arrays. A dendrogram of nearest neighbor analysis of 24 MuscleChip expression profiles shows that intra-patient tissue heterogeneity can be a greater source of experimental variability than inter-patient or age-dependent variation. The height of the branch-point of each tree reflects the extent of relatedness of the different profiles. The two profiles for each patient or mixed controls are from different regions of the same muscle biopsies.