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Table 1 Development of Diagnostic Rule 1.

From: A data review and re-assessment of ovarian cancer serum proteomic profiling

Consecutive M/Z M/Z Value Bin Range
Consecutive M/Z
Wilcoxon p-value Training Set Rule 1 Wilcoxon p-value
Entire Data Set
6782 4003.645 6781–6783 1.8685E-12 S 8.98721E-27
2311 464.3617 2308–2314 3.6867E-17 S 6.76511E-34
2237 435.0751 2234–2242 6.822E-18 S 3.895E-37
2193 418.1136 2190–2196 5.6991E-18 S 3.91174E-34
2171 409.7594 2170–2172 3.6168E-12   3.28383E-25
1736 261.8864 1734–1739 1.9206E-18 S 1.22566E-35
1681 245.53704 1673–1691 2.2891E-19 S 7.24111E-38
1600 222.4183 1598–1608 1.8911E-16   2.01896E-33
1594 220.7513 1593–1596 2.3886E-14   5.52587E-30
576 28.70048 562–582 6.82E-12   2.60148E-24
544 25.58989 541–547 1.9179E-14   8.67451E-30
181 2.7921478 181–183 1.2929E-13 S 1.21243E-27
  1. Consecutive M/Z is the numerical order of the M/Z value between 1 and 15,154. The M/Z values were sorted by p-values and the lowest 100 were arbitrarily selected. The M/Z values were then binned as described in the text, and the most significant consecutive M/Z score from each of the 12 bins was selected. M/Z values that were selected by the stepwise discriminant analysis are designated a "S" in the Rule 1 column. The Wilcoxon p-values calculated from the training set (used to derive the rule) and calculated from the entire data set are shown in their respective columns.