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Table 1 Development of Diagnostic Rule 1.

From: A data review and re-assessment of ovarian cancer serum proteomic profiling

Consecutive M/Z

M/Z Value

Bin Range

Consecutive M/Z

Wilcoxon p-value Training Set

Rule 1

Wilcoxon p-value

Entire Data Set

6782

4003.645

6781–6783

1.8685E-12

S

8.98721E-27

2311

464.3617

2308–2314

3.6867E-17

S

6.76511E-34

2237

435.0751

2234–2242

6.822E-18

S

3.895E-37

2193

418.1136

2190–2196

5.6991E-18

S

3.91174E-34

2171

409.7594

2170–2172

3.6168E-12

 

3.28383E-25

1736

261.8864

1734–1739

1.9206E-18

S

1.22566E-35

1681

245.53704

1673–1691

2.2891E-19

S

7.24111E-38

1600

222.4183

1598–1608

1.8911E-16

 

2.01896E-33

1594

220.7513

1593–1596

2.3886E-14

 

5.52587E-30

576

28.70048

562–582

6.82E-12

 

2.60148E-24

544

25.58989

541–547

1.9179E-14

 

8.67451E-30

181

2.7921478

181–183

1.2929E-13

S

1.21243E-27

  1. Consecutive M/Z is the numerical order of the M/Z value between 1 and 15,154. The M/Z values were sorted by p-values and the lowest 100 were arbitrarily selected. The M/Z values were then binned as described in the text, and the most significant consecutive M/Z score from each of the 12 bins was selected. M/Z values that were selected by the stepwise discriminant analysis are designated a "S" in the Rule 1 column. The Wilcoxon p-values calculated from the training set (used to derive the rule) and calculated from the entire data set are shown in their respective columns.