Table 1 Agreement of significant genes between "virtual" pooling and no pooling with data from one real experiment. Note: total number of "genes" on the chip = 8799, α = 0.05. Pool size=number of subjects per chip (# subjects per group/ # chips per group)
From: Statistical implications of pooling RNA samples for microarray experiments
Pool size | # of subjects per group | # of arrays per group | # of significant genes | % agreement between pooling and no pooling |
|---|---|---|---|---|
1 | 12 | 12 | 228 | Â |
2 | 12 | 6 | 152 | 67% |
3 | 12 | 4 | 108 | 47% |
4 | 12 | 3 | 111 | 49% |