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Table 2 Multiple-Run Comparisons of OSLEM and EM:

From: Optimal Step Length EM Algorithm (OSLEM) for the estimation of haplotype frequency and its application in lipoprotein lipase genotyping

Table 2.1 Multiple-Run Maximum λ = 2 Precision: 1e-7 Run: 1000 times

SNPs #

OSLEM

EM

OSLEM : EM

12

3m10.30s

5m4.43s

62.51%

13

8m20.61s

14m33.71s

57.30%

14

11m29.68s

20m38.47s

55.69%

15

12m50.12s

23m38.03

54.31%

16

37m58.03s

1h17m41.10s

48.87%

Table 2.2 Multiple-Run Maximum λ = 2 Precision: 1e-7 Run: 100 times

SNPs #

OSLEM

EM

OSLEM : EM

12

19.59s

28.51s

65.21%

13

54.18s

88.05s

61.53%

14

65.65s

118.96s

55.19%

15

75.65s

130.90s

57.79%

16

228.39s

426.47s

53.55%