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Figure 12 | BMC Bioinformatics

Figure 12

From: Visualisation and graph-theoretic analysis of a large-scale protein structural interactome

Figure 12

The top 25% superfamilies according to interaction rank form a highly connected component (left). The superfamily alpha/beta-Hydrolases (c.69.1) has only four interaction partners, but has nonetheless a good interaction rank, as its neighbourhood consists of two good nodes (Galactose-binding domain-like (b.18.1) and Lipase/lipooxygenase domain (PLAT/LH2 domain) (b.12.1)) and two medium nodes (Prolyl oligopeptidase, N-terminal domain (b.69.7) and HAD-like (c.108.1)). From top-left to bottom-right: b.1.4, beta-Galactosidase/glucuronidase domain; b.77.2, delta-Endotoxin (insectocide), middle domain; c.1.8, (Trans)glycosidases; b.18.1, Galactose-binding domain-like; b.69.7, Prolyl oligopeptidase, N-terminal domain; b.69.1, Galactose oxidase, central domain; c.69.1, alpha/beta-Hydrolases; c.108.1, HAD-like; b.1.1, Immunoglobulin; b.12.1, Lipase/lipooxygenase domain (PLAT/LH2 domain); a.119.1, Lipoxigenase; a.124.1, Phospholipase C/P1 nuclease

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