Flowchart outlining the relationship between the OXBench data sets and subsets. A non-redundant set of 218 structural domain families leads to the Master data set of 672 families by following the method outlined in Figure 1. The Master Data Set has additional sequences added to it to make the "Extended Data Set" and the sequences in the Master Data Set are made full-length in order to create the "Full-length Sequence Data Set". The Master Data Set is subdivided to create the test and training data sets as well as a set of two-sequence families (Pairwise Families), families with 8 or less sequences (MSA Data Set) and a set of families with more than two sequences in each family (Multiple Families). These families provide a range of different test data for multiple and pairwise alignment methods.