Table 1 A sampling of the less common statistics calculated by Eval when comparing the output of TWINSCAN and GENSCAN on the "semi-artificial" gene set used in [1] to the gold standard annotation. Standard statistics such as gene and exon sensitivity and specificity are also calculated but are not shown.
From: Eval: A software package for analysis of genome annotations
| Feature | Statistic | TWINSCAN | GENSCAN |
|---|---|---|---|
| Transcripts | Exons Per Transcript | 6.46 | 5.93 |
| CDS Overlap Specificity | 96.55% | 70.59% | |
| CDS Overlap Sensitivity | 87.64% | 97.19% | |
| All Introns Matched Specificity | 26.90% | 8.60% | |
| All Introns Matched Sensitivity | 21.91% | 10.67% | |
| Start and Stop Codon Specificity | 44.14% | 17.65% | |
| Start and Stop Codon Sensitivity | 35.96% | 21.91% | |
| Initial Exons | Overlap Specificity | 70.16% | 35.47% |
| Overlap Sensitivity | 77.54% | 73.91% | |
| Terminal Exons | 5' Splice Specificity | 74.36% | 36.22% |
| 5' Splice Sensitivity | 74.64% | 71.01% | |
| Introns | 80% Overlap Specificity | 73.11% | 48.07% |
| 80% Overlap Sensitivity | 80.19% | 72.58% | |
| Nucleotides | Correct Specificity | 84.61% | 64.76% |
| Correct Sensitivity | 84.26% | 88.87% | |
| Splice Acceptors | Correct Specificity | 77.23% | 52.69% |
| Correct Sensitivity | 84.90% | 81.30% | |
| Splice Donors | Correct Specificity | 76.18% | 53.02% |
| Correct Sensitivity | 84.63% | 80.19% | |
| Start Codons | Correct Specificity | 61.97% | 34.90% |
| Correct Sensitivity | 49.44% | 37.64% | |
| Stop Codons | Correct Specificity | 82.22% | 47.95% |
| Correct Sensitivity | 62.36% | 58.99% |