PathMAPA: a tool for displaying gene expression and performing statistical tests on metabolic pathways at multiple levels for Arabidopsis

Table 1 Statistical test of gene expression at pathway level.

Pathway Name	P-Value	Significant or not (NS)	Up or down regulation
ATP synthesis	0.02358	Significant	Up
Photosynthesis	0.04368	Significant	Up
Glutamate metabolism	0.00569	Significant	Up
Glyoxylate and dicarboxylate metabolism	1.0E-4	Significant	Up
Carbon fixation	1.0E-4	Significant	Up
Proteasome	0.02033	Significant	Up
Oxidative phosphorylation	0.001279	Significant	Down
Tyrosine metabolism	0.02515	Significant	Down
Glycolysis or Gluconeogenesis	0.515	NS
Citrate cycle (TCA cycle)	0.5626	NS
Pentose phosphate pathway	0.5711	NS
Inositol metabolism	1.0	NS
Pentose and glucuronate interconversions	0.7458	NS
Fructose and mannose metabolism	1.0	NS
Galactose metabolism	0.3579	NS
Ascorbate and aldarate metabolism	0.8625	NS
Fatty acid biosynthesis (path 2)	1.0	NS
Fatty acid metabolism	0.101	NS
Sterol biosynthesis	0.4255	NS
Bile acid biosynthesis	0.4304	NS
Ubiquinone biosynthesis	0.08707	NS
Androgen and estrogen metabolism	0.6917	NS
Urea cycle and metabolism of amino groups	0.6471	NS
Purine metabolism	0.8689	NS

This is an example to identify pathways that are affected by experimental treatment for one experiment with four replicates. NS: non-significant. Significance level is 0.05.

ISSN: 1471-2105