TY - JOUR AU - Wang, Junbai AU - Bø, Trond Hellem AU - Jonassen, Inge AU - Myklebost, Ola AU - Hovig, Eivind PY - 2003 DA - 2003/12/02 TI - Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data JO - BMC Bioinformatics SP - 60 VL - 4 IS - 1 AB - Using DNA microarrays, we have developed two novel models for tumor classification and target gene prediction. First, gene expression profiles are summarized by optimally selected Self-Organizing Maps (SOMs), followed by tumor sample classification by Fuzzy C-means clustering. Then, the prediction of marker genes is accomplished by either manual feature selection (visualizing the weighted/mean SOM component plane) or automatic feature selection (by pair-wise Fisher's linear discriminant). SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-4-60 DO - 10.1186/1471-2105-4-60 ID - Wang2003 ER -