From: Graph-based iterative Group Analysis enhances microarray interpretation
Down-regulated genes using GeneOntology-based network | Â | ||||
---|---|---|---|---|---|
anchor locus | group description | minimal p-value | E-value | N | max. rank |
YHL015W | ribosomal proteins and rRNA processing | 5.87E-86 | <0.01 | 39 | 48 |
YMR217W | amino acid and nucleotide biosynthesis | 3.38E-13 | 2.7 | 9 | 172 |
YDR144C | cell wall biogenesis | 4.06E-08 | 4.5 | 6 | 242 |
YNL065W | membrane transporter | 4.02E-05 | 9.3 | 3 | 141 |
YLR062C | bud site selection | 6.41E-05 | 9.9 | 4 | 367 |
YGL225W | protein glycosylation in Golgi | 1.12E-04 | 10.8 | 4 | 422 |
YPR074C | pentose phosphate pathway | 1.44E-04 | 11.2 | 4 | 449 |
total genes measured in network: 4087. | Â | Â | Â | Â | Â |
Down-regulated genes using metabolic network | Â | Â | Â | Â | |
anchor locus | group description | minimal p-value | E-value | N | max. rank |
YNL141W | nucleotide and amino acid biosynthesis, tRNA synthetases | 4.67E-59 | <0.01 | 39 | 45 |
YOR224C | RNA polymerases | 2.59E-13 | 1.1 | 23 | 219 |
total genes measured in network: 744. | Â | Â | Â | Â | Â |
Up-regulated genes using GeneOntology-based network | Â | Â | |||
anchor locus | group description | minimal p-value | E-value | N | max. rank |
YER065C | TCA and glyoxylate cycle, respiratory chain | 8.57E-77 | <0.01 | 39 | 66 |
YKL217W | membrane transporters (sugar, amino acids) | 1.76E-15 | 2.3 | 8 | 62 |
YAL017W | protein kinases | 1.07E-07 | 4.8 | 6 | 284 |
YBL043W | cell wall biogenesis | 3.81E-07 | 5.4 | 4 | 103 |
YGR248W | carbohydrate metabolism | 5.66E-07 | 5.5 | 5 | 232 |
YEL011W | glycogen metabolism | 1.01E-06 | 5.8 | 3 | 42 |
YER037W | protein phosphatases | 1.07E-06 | 5.8 | 8 | 736 |
YJL137C | glycogen biosynthesis | 7.46E-06 | 7.3 | 4 | 215 |
YDL085W | disulfide oxidoreductases | 1.05E-05 | 7.6 | 4 | 234 |
YNL173C | mating signal transduction | 1.65E-05 | 8.2 | 4 | 262 |
YNL134C | alcohol dehydrogenase | 1.34E-04 | 11.1 | 3 | 210 |
YBL038W | mitochondrial large ribosomal subunit | 1.99E-04 | 11.9 | 4 | 487 |
total genes measured in network: 4087. | Â | Â | Â | Â | Â |
Up-regulated genes using metabolic network | Â | Â | Â | Â | |
anchor locus | group description | minimal p-value | E-value | N | max. rank |
YER065C | TCA and glyoxylate cycle, respiratory chain | 4.96E-53 | 0.11 | 39 | 54 |
YGR088W | cytochrome c oxidase | 3.09E-10 | 1.2 | 11 | 106 |
YFR015C | glycogen synthases | 2.08E-04 | 3.6 | 3 | 45 |
YJR073C | methyltransferases | 3.85E-04 | 4.0 | 5 | 156 |
YDR001C | trehalases | 5.01E-04 | 4.2 | 3 | 60 |
YCR014C | DNA and RNA polymerases | 5.44E-04 | 4.2 | 17 | 481 |
YIR038C | glyoxalases | 8.64E-04 | 4.5 | 5 | 183 |
total genes measured in network: 744. | Â | Â | Â | Â | Â |