Figure 3From: Estimates of statistical significance for comparison of individual positions in multiple sequence alignmentsComparison of residue frequencies in multiple alignments of sequence homologs to the structure-based frequency predictions. A. Histogram of P-values (log-log scale). B. Difference in residue frequencies between 0.3% alignment positions with lowest P-values and the whole population. Frequencies of glutamate and aspartate show the greatest elevation.Back to article page