Distribution of false positive, true positive, sensitivity and specificity as functions of bits score (Fig. 2A), E-value (Fig. 2B) and identity (Fig. 2C). The bars for the distribution of false positive and true positive indicate the corresponding number of CDSs in a given interval of the statistic parameter (5 for bits score, 1 for -log(E-value) and 0.01 for identity) divided by the number of all false positive or true positive CDSs submitted for analysis. The lines show the specificity and sensitivity change along the cut-off scoring values.