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Table 2 Effects of different scoring criteria on CDS identification in the genome of S. typhimurium using IdentiCS and the database SWISS-PROT and TrEMBL. Criteria 1: E-value < = E-10; Criteria 2: E-value < = E-10 and Bits score > = 75; Criteria 3: E-value < = E-10, Bits score > = 75 and Identities > = 25%

From: IdentiCS – Identification of coding sequence and in silico reconstruction of the metabolic network directly from unannotated low-coverage bacterial genome sequence

  Criteria 1 Criteria 2 Criteria 3
True positive 4339 4305 4303
False positive 987 602 555
False negative 110 144 146
Sensitivity % 97.5 96.8 96.7
Specificity % 81.5 87.7 88.6