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Figure 2 | BMC Bioinformatics

Figure 2

From: MUSCLE: a multiple sequence alignment method with reduced time and space complexity

Figure 2

Profile-profile alignment. Two profiles (multiple sequence alignments) X and Y are aligned to each other such that columns from X and Y are preserved in the result. Columns of indels (gray background) are inserted as needed in order to align the columns to each other. The score for aligning a pair of columns is determined by the profile function, which should assign a high score to pairs of columns containing similar amino acids.

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