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Table 4 CPU times. The total CPU time required to create all alignments in each test set, measured in seconds on a 2.5 GHz Pentium 4 desktop computer.

From: MUSCLE: a multiple sequence alignment method with reduced time and space complexity

Method PREFAB BAliBASE SABmark SMART
MUSCLE-fast 540 11 45 30
FFTNS1 720 16 70 46
MUSCLE-prog 3,000 52 429 180
MUSCLE 11,000 81 1,500 560
POA-blast 11,000 90 290 670
CLUSTALW 15,000 160 210 480
POA 24,000 130 380 880