Artificial neural network approach for selection of susceptible single nucleotide polymorphisms and construction of prediction model on childhood allergic asthma

Table 3 Ranking of SNPs selected by PDM.

SNP	P-value^a	n (/5)^b	point (/50)^c
IL-4Rα (148 G/A)	0.0155	5	47
CysLT2 (2534 A/G)	0.5664	5	38
IL-10 (-571 C/A)	0.1074	5	27
C 3 (4896 C/T)	0.7205	4	27
C 3 (1692 G/A)	0.6993	2	18
IKAP (2446 A/C)	0.7988	5	17
IL-13 (329 G/A)	0.7924	4	16
C 3 (912 G/A)	0.5020	3	16
STAT6 (2964 G/A)	0.7881	2	14
IL-4 (-590 C/T)	0.9085	2	13
.........................................................................................................................................................................................................................................................
IKAP (3473 C/T)	0.2779	2	12
ADRB2 (265 A/G)	0.0541	4	8
IKAP (3214 T/A)	0.2997	2	8
C5aR (1289 C/A)	0.1211	1	6
C 5 (4266 G/A)	0.0581	1	5
CysLT2 (108 C/A)	0.0036	2	2
C3aR (1526 G/A)	0.7366	1	1

The 10 SNPs over the dotted line were used for the following experiments.
^aP-value was calculated with χ²test.
^bNumber of SNPs selected within last 10 input variables during PDM procedure (5 trials performed).
^cPoint of SNPs selected within last 10 input variables during PDM procedure. The score of order ranged from 1 to 10 points, based on the significance order in 1 PDM procedure and totaled in 5 trials.

ISSN: 1471-2105