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Table 5 Number of effective combinations (N ef ) and its concentration ratio.

From: Artificial neural network approach for selection of susceptible single nucleotide polymorphisms and construction of prediction model on childhood allergic asthma

2-SNP combination

    

10 SNPa:15 SNPb

2 : 0

1 : 1

0 : 2

 

N comb

90

300

210

 

10

23

3

 

0.28

0.64

0.08

 

0.15

0.5

0.35

 

1.85

1.28

0.24

 

3-SNP combination

    

10 SNPa : 15 SNPb

3 : 0

2 : 1

1 : 2

0 : 3

N comb

360

2025

3150

1365

25

82

64

39

0.12

0.39

0.30

0.19

0.05

0.29

0.46

0.20

2.28

1.33

0.67

0.94

  1. aSelected by PDM
  2. bNot including 10 SNP selected by PDM
  3. cThe number of 2-SNP combination that satisfies the following conditions:P-value < 0.05 and ECV2<0.5.
  4. The number of 3-SNP combination that satisfies the conditions: P-value < 0.05 and ECV3 < 0.5.
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BMC Bioinformatics

ISSN: 1471-2105

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