Table 2 Sequences used for the negative control
Protein | Host organism | Evidence for non-allergenicity | Accession | Reference |
|---|---|---|---|---|
Amaranth seed albumin | Amaranthus hypochondriacus | IgG-response, but no raised IgE-levels, after administration (intranasal and intraperitoneal) of amaranth seed albumin to mice | GenPept CAA77664 | [14] |
T1 | Catharanthus roseus | No reaction of recombinant T1 in IgE-sera binding, basophile histamine release, and skin prick testing using patients allergic to the related birch pollen allergen Bet v 1 | Not applicable | [15] |
Mite ferritin heavy chain | Dermatophagoides pteronyssinus | Reaction of mite ferritin with IgG, but not with IgE, of sera from patients allergic to house dust mite | GenPept AAG02250 | [16] |
Maltose binding protein | Escherichia coli | No reaction with IgE-sera from patients allergic to natural rubber latex (maltose binding protein used as part of fusion proteins with latex allergens) | SwissProt P02928 | [17] |
Human serum albumin | Homo sapiens | No reaction of human serum albumin with IgE-sera of patients allergic to cat- and porcine-serum albumin | SwissProt P02768 | [18] |
Human heat shock protein 70 | Homo sapiens | No reaction of human heat shock protein 70 with IgE-sera of patients allergic to heat shock protein 70 from Echinococcus granulosus | SwissProt P08107 | [19] |
Human beta-2-glycoprotein I | Homo sapiens | Presence of IgM antibodies, but not of IgE antibodies, directed against human beta-2-glycoprotein I in sera from atopic eczema/dermatitis patients | SwissProt P02749 | [20] |
Guayule rubber particle protein | Parthenium argentatum | No cross-reactivity between proteins from guayule and latex using IgE-sera from patients allergic to latex | Swissprot Q40778 | [21] |
Purple acid phosphatase 1 | Solanum tuberosum | Stimulation of IgG-, but no or only low stimulation of IgE-antibodies following administration of potato acid phosphatase to mice (oral and intraperitoneal) | TrEMBL Q6J5M7 | [22] |
Purple acid phosphatase 2 | Solanum tuberosum | See above | TrEMBL Q6J5M9 | [22] |
Purple acid phosphatase 3 | Solanum tuberosum | See above | TrEMBL Q6J5M8 | [22] |
Potato lectin | Solanum tuberosum | Stimulation of IgG-, but no or only low stimulation of IgE-antibodies following administration of potato lectin to mice (intraperitoneal) | TrEMBL Q9S8M0 | [23] |