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Table 2 Mean error (ME), root-mean-squared error (RMSE) and correlation coefficient (r) of models in the validation set. Success rates (SR) for efficacy higher than 0.75 or below 0.25 are also given for each feature selection method.

From: Profiled support vector machines for antisense oligonucleotide efficacy prediction

Methods

SVR

P-SVR

Selection

All feats.

MI(β = 0.75)

RFE

RFE

RFE

CV method

-

-

-

8-fold

-RNA

-RNA

r

0.356

0.367

0.374

0.398

0.430

0.440

ME

-0.0280

-0.0223

-0.0104

-0.0068

0.031

0.022

RMSE

0.312

0.300

0.301

0.299

0.299

0.278

SR >0.75

82.8

87.5

86.7

87.5

83.3

83.3

SR <0.25

71.4

73.9

71.4

73.9

76.2

82.9