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Table 1 The Outlier mRNA Set (Candidate Target List)

From: A population-based statistical approach identifies parameters characteristic of human microRNA-mRNA interactions

Transcription factors and other nucleic-acid binding proteins (15)

homeo box B8 (HOXB8)

E2F transcription factor 6 (E2F6)

transcription factor 20 (AR1) (TCF20)

DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 (DDX51)

similar to ATP-dependent RNA helicase DDX24 (DEAD-box protein 24) (LOC221311)

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1 (MLLT1)

high mobility group AT-hook 2 (HMGA2)

polymerase (DNA directed), theta (POLQ)

strand-exchange protein 1 (SEP1)

hypothetical protein FLJ12994 – RFX DNA-binding domain

similar to LINE-1 reverse transcriptase homolog (LOC285907)

similar to hypothetical protein (L1H 3 region) – related to reverse transcriptase

similar to putative p150 (LOC282945) – related to reverse transcriptase

similar to reverse transcriptase related protein (LOC222252)

similar to RTl1 (LOC376283) – related to reverse transcriptase

Kinases, receptors and other signaling proteins (13)

fyn-related kinase (FRK)

WNK kinase, lysine deficient 3 (PRKWNK3)

protein phosphatase 2, regulatory subunit B (B56), epsilon isoform (PPP2R5E)

EphA5 receptor (EPHA5)

killer cell lectin-like receptor subfamily A, member 1 (KLRA1)

polycystin and REJ (sperm receptor for egg jelly homolog, sea urchin)-like (PKDREJ)

integrin, alpha X (antigen CD11C (p150), alpha polypeptide) (ITGAX)

inositol 1,4,5-triphosphate receptor, type 1 (ITPR1)

hypothetical protein FLJ32810 – RhoGAP domain, SH3 domain

hypothetical protein FLJ00058 – G protein gamma 7

Rho GTPase-activating protein (RICS)

hypothetical protein FLJ30899 – probable ras GAP

similar to ADP-ribosylation factor-like membrane-associated protein (LOC132946) – ARF-like small GTPase domain, Sar1p-like member of the Ras-family

Membrane and extracellular proteins (11)

Laminin, beta 4 (LAMB4)

laminin, gamma 2 (LAMC2)

fibronectin 1 (FN1)

collagen, type IV, alpha 5 (Alport syndrome) (COL4A5)

collagen, type XIX, alpha 1 (COL19A1)

similar to Voltage-dependent anion-selective channel protein 1 (VDAC-1)

ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide (ATP1A2)

complement component 1, q subcomponent, beta polypeptide (C1QB)

hypothetical protein FLJ20506 – transmembrane protein

MAM domain containing glycosylphosphatidylinositol anchor 1 (MDGA1) – Ig, MAM domains

similar to TCAM-1 (LOC284171)

Cytoskeletal domain-containing proteins (7)

myosin heavy chain Myr 8 (MYR8)

ankyrin repeat domain 17 (ANKRD17)

KIAA1817 protein – intermediate filament, ATPase, PDZ, Band 4.1, FERM domains

chromosome 10 open reading frame 39 (C10orf39) – homologous to myosin, plectin

oxysterol binding protein 2 (OSBP2) – pleckstrin homology domain

KIAA1202 protein – PDZ, ATPase domains

hypothetical protein FLJ23529 – homolgous to dynein heavy chain

Miscellaneous or unknown function (26)

cell cycle progression 2 protein (CPR2)

olfactomedin 3 (OLFM3)

histidine rich calcium binding protein (HRC)

interferon-related developmental regulator 1 (IFRD1)

KIAA1301 protein – NEDD4-related E3 ubiquitin ligase NEDL2

KIAA1203 protein – ubiquitin C-terminal hydrolase

hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD)

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1)

KIAA1854 protein – leucine rich repeat C-terminal domains

testis specific, 14 (TSGA14)

chromosome 4 open reading frame 1 (C4orf1)-membrane AND nuclear protein

hypothetical protein FLJ33069

hypothetical protein FLJ38464

hypothetical protein LOC285431

hypothetical protein LOC284107

similar to agCP1362 [Anopheles gambiae str. PEST] (LOC344751)

KIAA1632 protein

similar to hypothetical protein D11Ertd497e (LOC343360)

LOC138724

LOC343460

LOC340963

LOC343220

LOC285842

LOC352767

LOC350293