Table 8 E. coli LSU rRNA is approximately 3350 nucleotides in length. The longest member of our test-set. The highest ranked Sfold prediction is remarkably poor, resolving just 5.8% of the reference structure.
From: A comprehensive comparison of comparative RNA structure prediction approaches
| Â | E. coli LSU rRNA: Single Sequence Methods | ||||
|---|---|---|---|---|---|
Algorithm | number of bps in reference | number of bps in prediction | True Positives (% sensitivity) | False Positives (% selectivity) | Correlation (%) |
RNAfold | 839 | 906 | 435 (51.8) | 430 (50.3) | 0.510 (51.1) |
Mfold (1) | 839 | 883 | 458 (54.6) | 383 (54.5) | 0.545 (54.5) |
Mfold (2) | 839 | 892 | 480 (57.2) | 364 (56.9) | 0.570 (57.0) |
Mfold (3) | 839 | 889 | 454 (54.1) | 392 (53.7) | 0.539 (53.9) |
Sfold (1) | 839 | 903 | 49 (5.8) | 811 (5.7) | 0.057 (5.8) |
Sfold (2) | 839 | 878 | 432 (51.5) | 411 (51.2) | 0.513 (51.4) |
Sfold (3) | 839 | 882 | 384 (45.8) | 463 (45.3) | 0.455 (45.6) |