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Table 8 E. coli LSU rRNA is approximately 3350 nucleotides in length. The longest member of our test-set. The highest ranked Sfold prediction is remarkably poor, resolving just 5.8% of the reference structure.

From: A comprehensive comparison of comparative RNA structure prediction approaches

  E. coli LSU rRNA: Single Sequence Methods
Algorithm number of bps in reference number of bps in prediction True Positives (% sensitivity) False Positives (% selectivity) Correlation (%)
RNAfold 839 906 435 (51.8) 430 (50.3) 0.510 (51.1)
Mfold (1) 839 883 458 (54.6) 383 (54.5) 0.545 (54.5)
Mfold (2) 839 892 480 (57.2) 364 (56.9) 0.570 (57.0)
Mfold (3) 839 889 454 (54.1) 392 (53.7) 0.539 (53.9)
Sfold (1) 839 903 49 (5.8) 811 (5.7) 0.057 (5.8)
Sfold (2) 839 878 432 (51.5) 411 (51.2) 0.513 (51.4)
Sfold (3) 839 882 384 (45.8) 463 (45.3) 0.455 (45.6)