Table 1 An example of co-occurring objects found in MEDLINE with a primary object of interest, capsaicin. A brief summary of what capsaicin is shown at top, with database objects of associated biomedical research interest in bold. Below are the MIM scores for each of these co-occurring objects, along with their relative rank in the list when sorted by score. A total of 2,069 objects co-occurred with capsaicin in the body of literature analyzed. Capsaicin is the active compound in chili peppers that causes their burning sensation. It acts upon a small family of capsaicin receptors, which have been found in sensory and vagal neurons, and allows a calcium influx into these cells causing them to fire and send heat-related signals to the CNS. Capsaicin can cause neurogenic inflammation upon application, and in high enough concentrations it is a neurotoxin.

From: Extending the mutual information measure to rank inferred literature relationships