Figure 3From: Network analysis of metabolic enzyme evolution in Escherichia coliCompound frequency distribution histogram for the metabolic network of E. coli. The 20 most promiscuous compounds have been removed in the network analyzed here. The histogram shows how many compounds (y-axis, logged scale) that occur with a certain frequency (x-axis) in the network. Compound frequency is defined as the number of times a compound occurs as part of an edge.Back to article page