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Table 4 The numbers of homologous enzyme pairs and enzyme pairs found at MPLs 1–12. The fraction is simply the ratio between the number of homologous enzyme pairs and the enzyme pairs. The reduced network is the network where the 20 most promiscuous compounds have been removed.

From: Network analysis of metabolic enzyme evolution in Escherichia coli

  WHOLE NETWORK REDUCED NETWORK
MPL HOMOLOGS ENZYME PAIRS FRACTION HOMOLOGS ENZYME PAIRS FRACTION
1 4.662 121,295 0.0384 429 6,035 0.071
2 2,982 452,081 0.0066 561 33,203 0.017
3 340 67,857 0.0050 1,115 105,254 0,011
4 5 2,861 0.0017 1,472 146,932 0.010
5 0 553 0 1,188 99,240 0.012
6 0 9 0 611 47,115 0.013
7 - - - 265 18,975 0.014
8 - - - 97 5,707 0.017
9 - - - 25 1,217 0.021
10 - - - 9 230 0.039
11 - - - 1 17 0.059
12 - - - 0 2 0
Total 7.989 644,656 0.0124 5,773 463,927 0.013