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Table 5 The numbers of functionally similar /dissimilar/undetermined homologous enzyme pairs at MPLs 1–11 in the network where the 20 most promiscuous compounds have been removed.

From: Network analysis of metabolic enzyme evolution in Escherichia coli

MPL

SIMILAR

DISSIMILAR

UNDETERMINED

 

NO. HOMOLOGS

%

NO. HOMOLOGS

%

NO. HOMOLOGS

%

1

240

56

90

21

99

23

2

233

42

207

37

121

22

3

515

46

395

35

205

18

4

693

47

553

38

226

15

5

579

49

469

40

140

12

6

326

53

231

38

54

8.8

7

146

55

101

38

18

6.8

8

74

76

22

23

1

1.0

9

20

80

5

20

0

0

10

9

100

0

0

0

0

11

1

100

0

0

0

0

Total

2836

49

2073

36

864

15