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Figure 5 | BMC Bioinformatics

Figure 5

From: Identification and utilization of inter-species conserved (ISC) probesets on Affymetrix human GeneChip® platforms for the optimization of the assessment of expression patterns in non human primate (NHP) samples

Figure 5

Intra- and interspecies reproducibility of expression signal intensities. Pair-wise correlation coefficients of 20 samples (12 human and 8 monkey (Rhesus macaque) samples) were calculated for expressed probesets (Figure 5A) and for expressed ISC probesets (Figure 5B). Correlation coefficients are visualized using colors of a heat spectrum (red=correlation coefficient of 0.5; white = correlation coefficient of 1.0). The graphs are symmetric along the diagonal lines. The diagonal line represents samples correlating with themselves, with a correlation coefficient of 1.0 (white). The means and standard deviations of correlation coefficients of human-human, monkey-monkey and human-monkey are shown in the bottom left, upper right and bottom right of each graph, respectively. A: Correlation coefficients calculated based on all expressed probesets. B: Correlation coefficients calculated based on expressed ISC probesets.

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