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Table 3 Summary of results after applying methods to three data sets For each data set, the selected model(s) with the chromosome arms classified in the tumor suppressor gene group and corresponding conditional probabilities of harboring a tumor suppressor gene are provided. A set of models was chosen such that models in the set had 2ln(Bayes factors) exceeding 2 when compared to models outside the set and 2ln(Bayes factors) less than 2 when compared to models within the set. A chromosome arm is in bold print if it has been identified in more than one data set.

From: A new mixture model approach to analyzing allelic-loss data using Bayes factors

Data Set

Model Chosen

Chromosome Arms Classified in TSG* Group (conditional probability)

Barrett

2 bb/bin

5q (1), 9p(0.962), 17p(1)

Gleeson

2 bb/bin

4q(0.982), 9p(0.916), 9q (0.813), 12q (0.859), 17p (0.998), 18q (0.954)

 

2 bin

4q(0.982), 9p(0.916), 9q (0.813), 12q (0.859), 17p (0.998), 18q (0.954)

 

1 bb

none

Hammoud

2 bb/bin

4q (0.968), 17p (0.994)

 

2 bin

4q (0.989), 17p (0.998)

  1. * TSG: tumor suppressor gene
  2. 2 bb: Two-component beta-binomial
  3. 2 bb/bin: Two-component beta-binomial/binomial
  4. 2 bin: Two-component binomial
  5. 1 bb: One-component beta-binomial
  6. 1 bin: One-component binomial