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Table 5 Set up hypothesis using linear contrasts

From: Analysis of oligonucleotide array experiments with repeated measures using mixed models

H o

L

Effects

Mean

D g1

D g2

R g1

R g2

(DR) g11

(DR) g12

(DR) g21

(DR) g22

(DR) gij = 0

(μ 21 - μ 11 ) - (μ 22 - μ 12 ) = 0

0

0

0

0

-1

1

1

-1

D gi = 0

(μ 11 + μ 12 ) - (μ 21 + μ 22 ) = 0

2

-2

0

0

1

1

-1

-1

R gj = 0

(μ 11 + μ 21 ) - (μ 12 + μ 22 ) = 0

0

0

2

-2

1

-1

1

-1

  1. The hypothesis in terms of model parameters and means were listed. The coefficients for the model parameters of the linear contrasts were determined for the corresponding hypotheses.