Plot of GCB-scores versus CU-contrast values for all genes of E. coli K-12 and the classification of compositional atypical genes. For all genes of the genomic data set, the two parameters were determined, converted to z-values and plotted as small dots. A high GCB-score is an indicator for adaptation to translational efficiency. Genes annotated as putatively alien according to the classification CA
and/or by using the MPW approach were labelled. The set CA
AND MPW consists of those genes identified as compositional atypical by both methods.