Table 1 The dataset of heterodimers.

Chain

Length

Contact area (Å ² )

Interacting residues

Type ^c

Start ^d

End ^d

Length ^e

1AM4-A

199

856.04

84–88, 119, 122, 123, 126, 127, 185, 189–194, 196–202, 205, 211–213, 215–218, 220

del., subst.

103

234

28

1AM4-D

174

958.07

511–513, 532–539, 556, 560–564, 566, 567, 570, 571, 586, 588, 592, 596

del., subst.

536

674

6

del., subst.

663

674

29

del., subst.

663

674

1

1BKD-R

166

1655.36

5, 12–18, 20, 21, 25, 30–35, 37, 40, 41, 54–71, 73, 95, 98, 99, 102, 103, 105

del., subst.

151

166

16

1C1Y-A

167

695.37

3, 21, 24, 25, 27, 29, 33, 34, 37, 38–42, 52, 54, 56, 63, 71

del., subst.

20

167

15

del., subst.

62

167

33

1C1Y-B

77

616.01

55, 57, 59, 62, 64–71, 73, 84, 85, 87–91

del.

70

131

0

1CXZ-A

182

892.09

0–3, 5, 25–29, 32, 43–48, 50, 52–54, 163–169, 172

del., subst.

52

181

38

del.

52

136

0

del., subst.

139

181

48

del., subst.

52

181

1

1E96-A

178

579.01

21, 22, 24–33, 36, 40, 41, 159–162

Ins.

75

76

19

del., subst.

13

178

18

del., subst.

76

178

40

1FIN-A

289

1609.88

37–50, 52–58, 69, 71–74, 76, 115, 116, 119–124, 150–159, 162, 179–183, 271–279

del.

163

196

0

del.

40

65

0

163

196

0

1FIN-B

260

1794.40

173–178, 181, 182, 185, 186, 189, 228, 230, 262, 263, 265–272, 274, 275, 288, 289, 292, 295–300, 302–309, 312–317

del., subst.

266

432

4

1I2M-A

165

1438.50

17–21, 23, 67–77, 91–103, 106–108, 110, 133, 134, 137, 138, 140

del., subst.

84

173

6

Ins.

83

84

17

del.

9

12

0

del., ins.

9

12

0

83

84

17

1I2M-B

388

1341.05

42, 44, 45, 55, 56, 75–77, 93–96, 106, 109, 128, 129, 147–152, 181, 200, 201, 249, 250, 266, 268–271, 278, 279, 303, 304, 320, 322, 323, 325, 334, 354, 355, 371, 373, 374, 382, 384, 407–409

del., subst.

182

411

5

Ins.

43

44

17

Ins.

43

44

31

ins., del., subst.

43

44

17

182

411

5

1IBR-B

458

1646.59

7, 10–15, 18, 19, 21, 22, 25, 26, 51, 52, 55–60, 62, 63, 66–69, 72, 76, 104–108, 110, 111, 114, 155–157, 159, 160, 189, 199, 200, 232, 235, 239, 246, 273–275, 277, 278, 281, 284, 285, 288, 335, 336, 339–343, 350, 354

del.

233

334

101

del.

263

334

71

1LFD-A

87

583.07

18, 20, 27–35, 51–54, 56

del., subst.

37

100

17

1WQ1-G

320

1391.63

745, 746, 749, 750, 782–793, 795, 796, 799, 802, 803, 831, 833, 894–898, 901–904, 906, 907, 910, 911, 914, 927, 928, 931, 934, 935, 938, 939, 942, 944, 947–952

del., subst.

897

1037

15

2TRC-P

212

2251.56

14–26, 28–30, 32, 33, 62–71, 77, 80, 85, 90, 93–95, 97, 99, 102, 105, 132, 135, 193, 194, 196–201, 207, 219, 220, 222–230

del

14

52

0

2TRC-B

340

2175.25

8, 12, 42, 44–48, 55–57, 59, 75–77, 96–101, 116–119, 143–148, 161–164, 184–186, 188, 203–206, 226–230, 246, 266, 268, 270–274, 288–292, 295, 304, 306–317, 332, 333, 335, 337, 339

del

20

33

0