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Table 1 Selected potential cleavage sites in human proteins from the Swiss-Prot database examined in this work. Columns represent Swiss-Prot identifier, predicted cleavage site position of P1 in the target protein, cleavage site score, and cellular localisation of target protein (Cyt – cytoplasmic, Nuc – nuclear, Mem – membrane associated). The last column lists the cleavage site in the sequence – cleavage is predicted between the central glutamine residue (Q) and the following amino acid residue. Sorted by prediction score.

From: Coronavirus 3CLproproteinase cleavage sites: Possible relevance to SARS virus pathology

Swiss-Prot ID

Loc

Position

Score

Sequence

AT6B_HUMAN

Nuc

358

0.916

EARLQ AVLAD

INI2_HUMAN

Mem

97

0.890

VATLQ SLGAG

PO21_HUMAN

Nuc

62

0.874

GTSLQ AAAQS

IRA1_HUMAN

Cyt

457

0.859

QSTLQ AGLAA

CFTR_HUMAN

Mem

762

0.842

GPTLQ ARRRQ

SCAD_HUMAN

Mem

22

0.828

GSHLQ AAAQT

P532_HUMAN

Nuc

308

0.782

ASVPQ STGNA

RPC1_HUMAN

Cyt

195

0.765

SNFLQ SFETA

P531_HUMAN

Nuc

196

0.738

KEQLQ SVTTN

T2D1_HUMAN

Nuc

741

0.730

GQLLQ AFENN

P532_HUMAN

Nuc

197

0.725

KAALQ QKENL

RPA1_HUMAN

Cyt

329

0.704

TVNLQ AVMKD

CFTR_HUMAN

Mem

958

0.693

HSVLQ APMST

MAE1_HUMAN

Cyt

64

0.661

KVKFQ AKLEH

MAE3_HUMAN

Cyt

64

0.661

KVKFQ AKLEH

P531_HUMAN

Nuc

410

0.660

QKKLQ SGEPV

CFTR_HUMAN

Mem

890

0.654

NTPLQ DKGNS

P532_HUMAN

Nuc

722

0.624

SPNLQ NNPEE

T2DT_HUMAN

Nuc

133

0.619

PSSVQ SVAVP

T2D3_HUMAN

Nuc

610

0.570

SSGKQ STETA

MAP4_HUMAN

Cyt

1005

0.519

YSHIQ SKCGS