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Table 4 Summary of hole-filling results.

From: A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases

 

Pathway/Genome Database

 

MtbRv

Caulo

Vcho

missing reactions w/ isozyme seqs

195

162

156

putative enzymes found at P > 0.9

84

71

82

fillers with borderline P (0.5 to 0.9)

37

17

11

holes with no BLAST hits

8

7

7

holes filled with ORFs at P > 0.8

9

2

6

newly completed pathways at P > 0.9

18

17

17

newly completed pathways at P > 0.8

20

14

17