Skip to main content

Table 1 Substitution rates derived from unconcatenated alignments. The table shows values obtained by averaging over individual in-frame alignments of sequence fragments. The alignments were derived from the chimpanzee BESs with and without the removal of low-quality sequence regions, annotated coding sequences retrieved from Genbank and coding sequence alignments derived from ESTs deposited in Genbank. Standard deviations from the mean are given in brackets.

From: FRAGS: estimation of coding sequence substitution rates from fragmentary data

Data Set Codons Codon identity K a K s K a /K s
BES (quality filtered) 13930 0.932 0.012 (0.023) 0.090 (0.520) 0.301 (0.43)
BES (unfiltered) 42477 0.935 0.022 (0.021) 0.076 (0.314) 0.500 (0.53)
Genbank CDSs 25488 0.966 0.010 (0.014) 0.028 (0.038) 0.461 (0.55)
Genbank ESTs 114759 0.972 0.008 (0.002) 0.048 (0.210) 0.235 (0.01)