Figure 2

Alignment of the predicted amino acids in the PfMB2 B domain with the amino-terminal domains of MB2 homologue translation products. Amino acids highlighted in black are conserved in all genes, those highlighted in gray are conserved in the majority of genes (at least four). A solid line underlines predicted signal peptides. A solid bracket above the Pf sequence delimits the antigenic region of PfMB2 [3]. A dotted line underlines the predicted S1 domain. A repeat region of PfMB2 is boxed. Alignment generated using the Clustal method (DNAStar) and manual alignment. Numbers in parenthesis indicate represented amino acids. Abbreviations are the same as in Figure 1.