The distributed structure of the Neisseria MLST and related databases. The profiles database contains all the allele sequences and allelic profiles (sequence types) and can be queried via network connections or directly through the web. The PubMLST isolate database encourages general submissions and represents the known diversity of strains. The MLST 107 and Czech 1993 isolate databases are also available through the Neisseria MLST website and contain reference  and project [11, 12] sets of isolate data (see site for further details). These isolate databases also retrieve information from non-MLST databases including those for PorA and FetA antigen typing and PubMed. Other private isolate databases (not shown) also make use of the profiles database.