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Figure 4 | BMC Bioinformatics

Figure 4

From: Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells

Figure 4

Control correction of each spot markedly improves the distribution of log ratios. (A) Histograms show that T/C and C/C log ratio distributions after lowess normalization still have a marked asymmetry with a larger tail towards the left (increased down-regulated genes). The distribution becomes symmetric after subtracting the log (C/C) from the log (T/C). (B) Quantile-quantile plots similarly show that the log ratio distribution becomes more normal after correction of each spot with the control ratio.

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BMC Bioinformatics

ISSN: 1471-2105

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