Both control correction and dye-swap methods reveal statistically significant changes in gene expression. Volcano plots of the control correction method (A) and the dye-swap method (B) reveal a small proportion of genes that met our arbitrary criteria of having >1.7 fold changes with p values <0.05, determined individually for each gene. The horizontal lines on each graph represent p = 0.05. The vertical lines represent 1.7 fold changes, both up- and down-regulated. Genes shown in blue in upper left and right areas were selected for northern blot confirmation.