Filtering high-throughput protein-protein interaction data using a combination of genomic features

BMC Bioinformatics

Table 3 Correlation coefficients of the genomic features for 100 random interactions

Genomic Features	r	t(98)	p-value
Homologous Interactions – Similar GO annotations	-0.12605	-1.2579	0.2401
Homologous Interactions – Interacting Pfam Domains	0.022501	0.222802	0.8826
Similar GO annotations – Interacting Pfam Domains	-0.01817	-0.17988	0.2868

r: Pearson's correlation coefficient; t(98): t-test with 98 degrees of freedom; p-value: probability. Since the p-value for all t-tests is greater than the significance level of 0.05, the null hypothesis, that the genomic features are not correlated, is accepted.

ISSN: 1471-2105