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Table 5 SSS results for xyna-theau and xynz-clotm. SSS results for the human kinases xyna-theau and xynz-clotm (BLAST identity score 41%, similarity 59%). Similar subsequences are shown where BLAST is not able to find appreciable similarity with pure character matching strategies. None of the good alignment detected by BLAST were found to be with high SSS scores. Only the sequences with low SSS scores but low BLAST alignments are shown. Figures in the last column are created by Magic Fit using the SPDBV software with real pdb files downloaded from the PDB Databank. F = 16, S z = 8, β = 2.5. PDBids : xyna-theau = 1GOR, xynz-clotm = 1XYZ. The assignments for secondary structure are: h = helix; b = residue in isolated beta bridge; e = extended beta strand; g = 310 helix; i = pi helix; t = hydrogen bonded turn; s = bend [37].

From: Detailed protein sequence alignment based on Spectral Similarity Score (SSS)

 

Seq

Segment

Subseq

msd

Blast Result

rms

Image

1

x-theau

x-clotm

(32) [259–267]

(30) [242–250]

3.89

0.76

fig 5a

2

x-theau

x-clotm

(36) [288–296]

(31) [245–253]

1.96

0.61

fig 5b

3

x-theau

x-clotm

(27) [215–223]

(20) [158–166]

2.45

0.17

fig 5c

4

x-theau

x-clotm

(20) [160–168]

(13) [103–111]

2.97

1.59

fig 5d