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Table 1 The average number of substitutions that occurred in transcription factor binding sites in genes at the tails and center of the distributions are shown. When normalized by the total substitution rate in these promoters, the enrichment of transcription factor binding site substitution detection is shown.

From: Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data

  Downregulated Unchanged Upregulated
Human 0.64 ± 0.25
enrichment: 1.48x
0.42 ± 0.01 0.92 ± 0.40
enrichment: 1.71x
Chimpanzee 0.48 ± 0.24
enrichment: 1.39x
0.59 ± 0.15 0.90 ± 0.28
enrichment: 1.36x