Figure 4
From: Considerations when using the significance analysis of microarrays (SAM) algorithm
FC effects individual q-values: q-values of all genes scored as significant in the brain aging study (reduced data set) at FC 1.51 at other FC settings. Genes only acquires discrete q-values and all 538 genes are shown, but overlap. (B) Running SAM with different FC settings changes the biological interpretation: Venn diagram comparing the number of significantly overrepresented classifications (EASE score <0.05) using the reduced brain aging data set analysed either with a 1.0 FC setting (314 genes) or a 1.5 FC setting (538 genes).